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Trans-targeting of human papillomavirus type-16 E6 and E7 transcripts by an engineered hairpin ribozyme
(Northern Illinois University, 1995)
Three hairpin ribozymes have been designed which cleave sequences from HPV-16 E6 and E7 transcripts in vitro. E6 and E7 proteins from high risk HPV types are capable of immortalizing human cells and are therefore considered ...