Browsing Dissertations and Theses by Author "Jakkaraju, Sriram"
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The thermodynamic dissection and design of high-affinity antibodies
Jakkaraju, Sriram (Northern Illinois University, 2015)Antibody fragments are attractive alternatives to conventional antibodies for both therapeutic and diagnostic applications. One example, single-domain VHH antibodies, which are derived from camelid heavy chain-only antibodies, ...