Caffeine and radiation induced mutations in drosophila melanogaster
Callaghan, Margaret Mary
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Muller-5 ferale Drosophila mlanogaeter were rated to three groups of Oregon R rales which were treated as follows: caffeine only; air treatment both during X-rad1at1on and as a post-treatment; caffeine treatment both during X-rad1at1on and as a post-treatment. The frequencies of sex-linked recessive lethal mutations In the F2 generation of each group were calculated. For immature sperm, spermatids, spermatocytes, and spermatogonia, the data indicated no significant differences between frequencies of genetic damage in cells X-rayed and post-treated in air and the above mentioned cells X-rayed and post-treated in caffeine and air. In the case of mature sperm, although the data are not quite significant, there was a decrease in frequencies of genetic damage in the caffeine treated cells as compared with the non-caffeine treated cells.