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CFD analysis of blood flow through stenosed arteries

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dc.contributor.advisor Majumdar, Pradip, 1954- en_US Surigala, Narmada en_US 2017-08-02T21:16:18Z 2017-08-02T21:16:18Z 2015
dc.description Advisors: Pradip Majumdar. en_US
dc.description Committee members: Abhijit Gupta; Meung Kim. en_US
dc.description.abstract The pathological complications of atherosclerosis, namely heart disease and stroke, remain the leading cause of mortality in the world. Cardiovascular illness is highly prevalent among the American population. One manifesto of cardiovascular disease is Peripheral Artery Disease (PAD) which is caused by atherosclerosis in the arteries. Atherosclerosis is a vascular disease that reduces arterial lumen size through plaque deposition and arterial wall thickening. The flow patterns in the arteries are highly modulating along with the cardiac cycle and a strong function of the waveform created by the heartbeat. In this study, a computational simulation model is developed to analyze blood flow distribution in a femoral artery network based on Navier-Stokes equation. A comparative analysis of blood flow through femoral artery is done based on Newtonian and non-Newtonian blood flow by using Carreau-Yasuda model subjected to a waveform based on a cardiac cycle. The non-Newtonian CFD flow analysis model is use to analyze blood flow distributions in a femoral artery along with the adjacent capillary porous tissue medium. This simulation model is used to analyze the flow and stress field in a healthy and atherosclerosis affected femoral arteries. Velocity, pressure and Wall Shear Stress fields over cardiac cycle are analyzed to demonstrate that adverse flow field created upstream and downstream of the blockage that may cause enhanced growth in size of the blockage. en_US
dc.format.extent 79 pages en_US
dc.language.iso eng en_US
dc.publisher Northern Illinois University en_US
dc.rights NIU theses are protected by copyright. They may be viewed from Huskie Commons for any purpose, but reproduction or distribution in any format is prohibited without the written permission of the authors. en_US
dc.subject.lcsh Regional blood flow--Measurement--Computer simulation en_US
dc.subject.lcsh Regional blood flow--Measurement--Mathematical models en_US
dc.subject.lcsh Femoral artery en_US
dc.subject.lcsh Mechanical engineering en_US
dc.subject.lcsh Biomedical engineering en_US
dc.title CFD analysis of blood flow through stenosed arteries en_US
dc.type Text en_US
dc.contributor.department Department of Mechanical Engineering en_US M.S. (Master of Science) en_US

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