Erythrocyte antigens in the current NIU Phasianus colchicus colony
Langdon, John L.
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This thesis assessed erythrocyte antigens segregating in the current NIU ringnecked pheasant, Phasianus colchicus (Phco), colony. Recently a minimum of 14 Phco- B haplotypes were delineated in the closed NIU pheasant colony. Alloimmunizations within pheasant families were designed to maintain and expand on the pheasant B-system data. It is possible that past and present antisera detected nine Phco-B haplotypes that corresponded to those previously designated, except la. One antiserum, in particular, specifically detected the B2 antigen in the NIU chicken colony and the B21 antigen o f chickens derived from the Heisdorf Nelsen stock. Evidence is presented that supports the possibility o f non-MHC systems segregating in the current N IU pheasant colony. Alloimmunizations within pheasant families detected a minimum o f four haplotypes segregating together in a system designated as X. In addition, chicken anti-chicken antisera specific for antigens of the chicken A and C blood group systems were selectively absorbed with pheasant erythrocytes. The segregation of these antigens in subsequent generations o f pheasants suggests a pattern o f alternate segregation of antigens produced by alleles at two separate loci. Thus, in the pheasant there appear to be three non-MHC alloantigen systems. Finally, antisera produced in Ancona chickens by donor chicken-pheasant hybrids lend further evidence to the existence of multiple non-MHC blood groups segregating in the current NIU Phasianus colchicus colony.